The land use and land cover change is a problem which affects mostly tropical developing countries such as Colombia. Drivers of these changes are both direct and indirect, and exogenous or endogenous and include agricultural expansion, deforestation, climate change, and national and international policies. Drivers are divided according to the grade of expansion and the level of influence on the land. This project proposal evaluated the uses of the land in Colombia, the constraints, land cover, farming distribution, and permanent crops and arable land, by percentage of intensity. Two specific sites were chosen in the departments of Cundinamarca and Tolima by using Terra-i software which identified the land cover and habitat change in real time every sixteen days from 2004 to 2011. The cover and uses of the land for each site are described along with the conflicts in the uses of land. In order to fully understand the issue, both the drivers and the causes of land use and land cover are given, in addition to case studies and photographs. The data was analysed in the field qualitatively through direct interviews to communities in both sites to verify information given by Terra-i. The results focus on the changes in the land use produced by increasing industrialization and overexploitation of the land. Drivers in the land use change are divided into demographic, institutional and technological development, and global environmental change conditions.